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Management of haemochromogenuria / myoglobinuria / haemoglobinuria

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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The management of myoglobinuria or haemoglobinuria is best carried out under the guidance of a renal physician.

Management steps include:

  • increasing a fluid challenge to ensure that the urine output is at least 1-2 mls/kg/hour
  • alkalinization of the urine:
    • reduces urinary crystallisation of haemochromogens
    • add sodium bicarbonate to the resuscitation fluid at 25 mmol/litre of fluids
  • forced diuresis:
    • mannitol added to the fluids
    • 12.5 g/litre of fluids

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