LDH in myocardial disease
Last reviewed 01/2018
LDH may rise following myocardial infarction and in myocarditis.
Following a myocardial infarction:
- levels increase after 12 to 24 hours
- peak at 48 to 72 hours
- return to normal after 8 to 10 days, providing there are no complications
- the peak reached is from two to ten times the upper reference limit
- the normal plasma LD1:LD2 isoenzyme ratio of less than 1.0 is reversed
Therefore, LDH provides a valuable late indicator of infarction. Assessment of LD1 and LD2 provide a more specific index of infarction.