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Latex allergy

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

An allergy to latex (the natural rubber latex protein in rubber) is an immediate hypersensitivity (IgE mediated) reaction. This means that the speed of onset of features of a latex allergy occur over a short period of time (seconds+ (up to 6 hours)). Dermatological manifestations include itching, burning skin and urticaria. There may be associated angioedema and and even anaphylaxis. Other possible features include laryngeal oedema, rhino - conjunctivitis, and wheezing.

Those individuals with increased susceptibility include:

  • history of atopy
  • spina bifida
  • multiple surgical procedures
  • history of fruit or vegetable allergy

Assessment:

  • detailed history
  • RAST - measurement of antibodies to latex - not always positive in latex allergy subjects (1)
  • if RAST is negative but there is a high index of suspicion then skin prick test should be undertaken - this should be undertaken in controlled conditions with resuscitation facilities available

Management:

  • explanation of the condition (to patient and family)
  • recommended carry adrenaline e.g. Epipen (R) - a patient should carry 2 Epipens (R) so that there is adrenaline available if the patient undergoes a late phase reaction some 6 hours after an immediate hypersensitivity reaction
  • patient should wear a medical alert talisman or bracelet
  • documentation of latex sensitivity in clinical notes
  • if patient has to wear material that potentially contain latex (e.g. gloves) in occupation then alternative material should be worn e.g. neoprene, dermaprene, PVC, nitrile, polythene, polyurethane, acrylics

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