In Guillain-Barre syndrome the suppressor T cell response is reduced suggesting a cell-mediated immunological reaction directed at the peripheral nerves. Occasionally, serum antibodies to myelin components are detected.
Nerve damage occurs segmentally. Lymphocytes infiltrate the nerve roots and release cytotoxic substances that damage the Schwann cells and myelin. Myelin is removed by macrophages. If the axon is damaged, the nerve cell dies, and regeneration becomes impossible.
Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page