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Treatment

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Treatment is with synthetic human growth hormone, although other additional hormones may also be indicated.

Treatment with growth hormone in a child with growth hormone deficiency should be started as soon as possible after diagnosis.

There is evidence that treatment with synthetic growth hormone in a children with growth hormone deficiency:

  • produces a final height gain of 25-30cm (1)
  • almost 90% of children with growth hormone deficiency treated with synthetic growth hormone achieve an adult final height within the genetically determined target height range (2)

Growth hormone received a NHS license for use in the growth hormone deficient adult (3)

Reference:

  • The British Society for Paediatric Endocrinology and Diabetes and the Royal Colleges of Paediatrics and Child Health. Submission of evidence for the National Institute of Clinical Excellence health technology appraisal: the use of human growth hormone in children.
  • Thomas M et al. Final height in children with idiopathic growth hormone deficiency treated with recombinant human growth hormone: the Belgium experience. Horm Res 2001; 55:88-94.
  • Update (5/11/97), p.652-6.

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