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haemolytic uraemic syndrome

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Haemolytic uraemic syndrome is the triad of:

  • acute renal failure
  • microangiopathic haemolytic anaemia
  • thrombocytopenia

The thrombocytopenia is thought to be a consequence of platelet consumption at sites of endothelial injury. Despite this blood clotting times (prothrombin time, kaolin clotting time) are normal.

It is now believed that thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome represent a spectrum of disease.

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