Last reviewed 10/2022

Hypersplenism is an imprecise term commonly used to refer to a clinical state characterised by:

  • reduced red blood cells, platelets, and granulocytes in any combination
  • splenomegaly of any cause
  • an adequately cellular bone marrow - ie. indicating that there is sufficient compensation to cytopenia
  • totally or partially correctable by splenectomy

Symptoms include:

  • abdominal discomfort
  • anaemia
  • infection
  • bleeding