This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Transcranial doppler in sickle cell anaemia

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The risk of stroke is highest in children with sickle cell anaemia who have abnormally narrowed cerebral vessels. Narrowing of the large intracranial vessels results in increased velocity of blood flow.

In a study, blood flows in excess of 170 cm/sec were defined as abnormal. The relative risk of stroke in patients with abnormal intracranial doppler studies was 44 (95% confidence interval, 5.5 to 346).

The authors suggested that blood transfusion policy should be more aggressive in these high-risk patients.

Reference:

  • Adams R. et al. (1992). The use of transcranial ultrasonography to predict stroke in sickle cell disease. New Engl. J. Med. 326(9), 605-10.

Create an account to add page annotations

Create a free account

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.