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Osteosclerotic myeloma

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Osteosclerotic myeloma accounts for 3% of patients with myeloma. There is commonly an associated polyneuropathy which may form part of the POEMS syndrome.

Often there is a single plasmacytoma which secretes the paraprotein. Treatment consists of surgical removal of the tumour or radiotherapy.


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