This is a group of antibacterial antibiotics that are derived from the various species of Streptomyces, in which case they have the spelling -mycin, and micromonospora in which case the spelling is -micin.
They act by binding to the 30S ribosome and preventing proper functioning by leading to misreading of tRNA.
Included in this group are gentamicin and streptomycin.
Side effects include:
- aminoglycosides may cause vertigo
- streptomycin may cause nerve deafness