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This is a group of antibacterial antibiotics that are derived from the various species of Streptomyces, in which case they have the spelling -mycin, and micromonospora in which case the spelling is -micin.

They act by binding to the 30S ribosome and preventing proper functioning by leading to misreading of tRNA.

Included in this group are gentamicin and streptomycin.

Side effects include:

  • aminoglycosides may cause vertigo
  • streptomycin may cause nerve deafness


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