This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Triple response

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The triple response is a simple way of demonstrating the early phases of acute inflammation. A patch of skin is mechanically 'injured' by lightly scratching with a nail; it produces the sequential triad:

  • immediate local reddening due to vasodilatation secondary to the release of chemical inflammatory mediators, particularly histamine
  • surrounding red flare response due to chemical mediators stimulating local free nerve endings
  • weal response - local swelling - due to cytokines increasing local vascular permeability to give an exudate

Related pages

Create an account to add page annotations

Create a free account

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.