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Kinin system

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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The kinins are biologically-active polypeptides. They are formed by kallikrein-catalyzed cleavage of plasma kininogens, part of the alpha-2-globulin protein fraction.

Examples of kinins include bradykinin and kallidin. They may have a role in inflammation and exocrine gland secretion. Kinins cause vasodilation of most vessels but vasoconstriction of the pulmonary bed, and they also alter vascular permeability.


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