This site is intended for healthcare professionals
Login | Register (NOW FREE)

Medical search

Osler - Weber - Rendu syndrome

FREE subscriptions for doctors and students... click here
You have 3 open access pages.

Hereditary haemorrhagic telangiectasia is a rare autosomal dominant condition where multiple small telangiectases occur on the skin and mucous membranes, most commonly on the lips and the tongue. Lesions are also often scattered over the pulps of fingers. The size and number of lesions increases with age.

Epistaxis is the most common complaint.

When telangiectases are present in the gastrointestinal tract they may cause chronic blood loss with iron deficiency anaemia. Occasionally there may be torrential bleeding.

Arteriovenous malformations may occur in the:

  • liver
  • lungs, causing:
    • clubbing
    • murmurs
    • paradoxical emboli

Oestrogen may be used to reduce the severity and frequency of epistaxes (via induction of metaplasia of nasal mucosa).

Embolization may be used if there are pulmonary arteriovenous malformations.

Click here for an image of this condition

 

Links:

The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions LtdĀ®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions LtdĀ® receives funding from advertising but maintains editorial independence. GPnotebook stores small data files on your computer called cookies so that we can recognise you and provide you with the best service. If you do not want to receive cookies please do not use GPnotebook.