genetic counselling

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  • most patients with ankylosing spondylitis are HLA-B27 positive - the risk of transmitting the antigen to his/ her children is 50%

  • if a child is HLA-B27 positive then the chance of developing ankylosing spondylitis is 1 in 3

Reference:

  • (1) Update (1998), 57 (8), 697-703.

Last reviewed 07/2021