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Pellagra

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Pellagra is caused by deficiency of niacin and is classically characterised by four D's:

  • photosensitive dermatitis
  • diarrhoea
  • dementia
  • death

Other features include:

  • stomatitis
  • neuropathy
  • tremor
  • ataxia
  • fits
  • rigidity
  • depression

The neurological signs may be similar to those seen in subacute combined degeneration of the cord.

It is rare in the UK.


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