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Dandy-Walker syndrome

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Dandy-Walker Syndrome is a rare congenital abnormality in which there is usually an absence of the foramina of Magendie and Luschka.

It is characterised by:

  • cystic dilatation of the fourth ventricle due usually to absence of the foramina
  • dilatation of the third and lateral ventricles - but to a lesser extent than the fourth
  • enlargement of the posterior fossa with a high tentorium cerebelli and transverse sinuses
  • wide separation of the cerebellar hemispheres with a small vermis, displaced laterally
  • various other developmental abnormalities in 65% of patients

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