This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Clinical features

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Clinical features include:

  • non-thrombocytopenic purpura:
    • over the extensor surface of the buttocks and legs
    • rash is common and is often the presenting feature

  • other skin manifestations:
    • macules or papules
    • urticaria especially of the face and legs
    • lesions occur in crops and may be precipitated by abrading the skin

  • arthritis:
    • in up to two thirds of patients
    • affects large joints, flitting in nature
    • usually lasts only a few days

  • nephritis - mild focal segmental glomerulonephritis, proteinuria, microscopic haematuria

  • abdominal pain:
    • a common feature and may precede other symptoms
    • there may be melaena

  • localised oedema around orbits of eyes, backs of hands and feet

  • testicular inflammation in males

  • central nervous system involvement occurs rarely, and can result in fits and coma

Related pages

Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page