diabetes mellitus

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Diabetes mellitus is a heterogeneous collection of disorders unified by a state of diminished insulin action which may result from:

  • decreased insulin secretion
  • a reduction in the effectiveness of secreted insulin
  • a combination of the above

Diabetes mellitus, irrespective of its aetiology, is characterised by hyperglycaemia and is defined in terms of plasma glucose levels.

Last reviewed 08/2021