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blue sclerae

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Blue sclerae result from congenital thinning of the sclerae. The underlying epithelium shows through, giving a blue appearance.

Blue sclerae are most importantly associated with types I and II osteogenesis imperfecta, the latter of which is fatal and thus not seen in adult practice.

Other associations include:

  • Ehler's danlos syndrome
  • pseudoxanthoma elasticum
  • Marfan's syndrome

A blue sclera may also be acquired through long-term use of corticosteroids.


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