oral contraceptives and induced endometrial changes

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  • the COC may induce a wide variety of endometrial changes - a common reaction is a discordance between glandular and stromal tissues - the stromal reaction reminiscent of the decidua of pregnancy.
  • when the COC is discontinued then the endometrium reverts to normal.
  • endometrial changes associated with the COC have been minimised with the newer low-dose contraceptives

Last reviewed 01/2018