sporadic Creutzfeldt-Jacob disease

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Sporadic CJD accounts for over 90% of cases of human prion disease.

The disease occurs worldwide with an annual incidence of one case per million population.

There are no known environmental risk factors.

Most patients with sporadic CJD are homozygous for methionine at the polymorphic position 129 in the prion protein.

Last reviewed 01/2018