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Dopamine

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Dopamine acts on both dopamine and adrenergic receptors in a dose dependent manner.

Below 5 microgram per kg per min, dopamine acts mainly to increase renal blood flow by stimulating dopamine receptors.

At doses between 5 and 20 microgram per kg per min, there is greater beta-1 and alpha adrenoceptor stimulation, resulting in increased cardiac output and a modest rise in blood pressure.

At doses above 20 microgram per Kg per min, the alpha receptor effects are more marked, resulting in a further rise in blood pressure which is generally undesirable.


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