This site is intended for healthcare professionals
Login | Register (NOW FREE)

Medical search

Gardner's syndrome

FREE subscriptions for doctors and students... click here
You have 3 open access pages.

Gardner's syndrome is characterized by the presence of polyposis coli, soft tissue and bony tumours. It has an autosomal dominant inheritance (gene located on the long arm of chromosome 5).

Gardner's syndrome is associated with:

  • osteomas or exostoses of the mandible, skull and sinuses
  • epidermoid or sebaceous cysts
  • dermoid tumours, especially in abdominal incisions
  • postoperative mesenteric fibromatosis

Carriers of the gene have congenital hypertrophy of the retinal pigment epithelium (revealed as black spots on fundoscopic examination). This feature is valuable in aiding detection of carriers before the development of symptoms.

Presentation is usually with bloody diarrhoea (median age at onset is 20 years old).

Treatment measures include:

  • careful follow-up is required
  • subtotal colectomy and treatment (electrodesiccation) of rectal polyps


The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions LtdĀ®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions LtdĀ® receives funding from advertising but maintains editorial independence. GPnotebook stores small data files on your computer called cookies so that we can recognise you and provide you with the best service. If you do not want to receive cookies please do not use GPnotebook.