complications

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These include:

  • persistent fatigue – appears to be present in 9% to 22% of cases at six months after illness onset (1)
  • hepatitis - probably occurs in all cases and abnormal liver function tests are usual (2)
  • splenic rupture - in 0.1 to 0.2 % of cases (3)
  • thrombocytopaenia
  • haemolytic anaemia
  • cardiac involvement - 10% of patients develop minor T-wave changes
  • meningitis - benign
  • encephalitis - 33% mortality of an 11 case series
  • single nerve palsies
  • Guillain-Barre syndrome
  • depression and malaise
  • airway blocked by pharyngeal oedema - rare
  • nephritis - extremely rare and excellent prognosis
  • pneumonitis
  • acute interstitial nephritis (2)
  • myocarditis and cardiac conduction abnormalities (2)
  • neurologic abnormalities
  • cranial nerve palsies(2)
  • retrobulbar neuritis (2)

Infection may be fatal in males with the rare Duncan's syndrome.

Reference:

Last reviewed 01/2018

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