FSH/LH levels

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Ovarian failure is indicated by consistently raised FSH levels - over 30IU/l - together with raised LH and low serum oestradiol levels (1).

If a woman has symptoms typical of the menopause and has a slightly irregular menstrual cycle, then a raised FSH in the early follicular phase may indicate the perimenopause, and it is likely that the patient will become menopausal during the next five years.

NICE state (2):

  • FSH test:
    • do not use a serum follicle-stimulating hormone (FSH) test to diagnose menopause in women using combined oestrogen and progestogen contraception or high-dose progestogen

    • consider using a FSH test to diagnose menopause only:
      • in women aged 40 to 45 years with menopausal symptoms, including a change in their menstrual cycle

      • in women aged under 40 years in whom menopause is suspected

        • diagnose premature ovarian insufficiency in women aged under 40 years based on:
          • menopausal symptoms, including no or infrequent periods (taking into account whether the woman has a uterus) and
          • elevated FSH levels on 2 blood samples taken 4-6 weeks apart

Reference:

Last edited 02/2020 and last reviewed 02/2020