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Connective tissue disease

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Connective tissue disease may present with pyrexia of unknown origin. The long list of possible causes includes:

  • rheumatoid arthritis
  • systemic lupus erythematous
  • polyarteritis nodosa
  • temporal arteritis
  • Still's disease
  • Wegener's granulomatosis
  • "non-specific vasculitis"
  • acute rheumatic fever
  • polymyalgia rheumatica
  • polymyositis

These may cause a PUO which lasts for more than three weeks.

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