brush border enzyme defects

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Isolated defects in brush border enzymes and transport proteins cause specific malabsorption, for example:

  • lactose intolerance
  • sucrase-isomaltase deficiency
  • glucose-galactose malabsorption
  • Hartnup disease } also produce amino-aciduria as renal
  • cystinuria } tubule cells share same transport } mechanisms

Last reviewed 01/2018

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