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Elevation of ALP in normal individuals

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Alkaline phosphatase may be chronically elevated in normal individuals in the following circumstances:

  • following a fatty meal in people with O or B blood groups

  • third trimester of pregnancy

  • possibly as a familial trait

  • fast-growing adolescents

  • elderly - alkalilne phosphatase levels normally increase gradually between the ages of 40 and 65 years, especially in women; the normal alkaline phosphatase level in an otherwise healthy 65-year old woman is more than 50% higher than the level in a healthy 30-year old woman (1)

Benign transient hyperphosphatasia - see linked item.

Reference:

  • 1) Wolf PL (1978). Clinical significance of an increased or decreased serum alkaline phosphatase. Arch Pathol Lab, 102, 497-501.

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