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  • combined high dose vitamin E and vitamin A therapy does confer protection against severe retinal degeneration, fundoscopic and functional retinal changes have been demonstrated, suggesting a role for other factors, including polyunsaturated fatty acid deficiency and ongoing oxidative damage


  • (1) Granot E, Kohen R.Oxidative stress in abetalipoproteinemia patients receiving long-term vitamin E and vitamin A supplementation, Am. J. Clin. Nutr. 2004;79: 226-230.

Last reviewed 01/2018