This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

First line investigations

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The following tests should be performed in patients with asymptomatic elevation of aminotransferase levels:

  • serology for hepatitis C:
    • presence of antibody to the hepatitis C virus indicates chronic hepatitis C

  • serology for hepatitis B surface and core antigens:
    • presence of antibodies to hepatitis B surface and core antigens indicates chronic hepatitis B

  • serum iron and total iron binding capacity:
    • increased iron load suggests haemochromatosis

  • serum caeruloplasmin levels:
    • decreased levels suggest Wilson's disease

  • serum protein electrophoresis:
    • increase polyclonal immunoglobulin suggests autoimmune hepatitis
    • decreased alpha-globulin suggests alpha-1 antitrypsin deficiency

  • liver autoimmune serology (especially if female)

Related pages

Create an account to add page annotations

Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page