This site is intended for healthcare professionals
Login | Register (NOW FREE)

Medical search

erythema infectiosum

FREE subscriptions for doctors and students... click here
You have 3 open access pages.

Parvovirus B19 virus, discovered accidentally in 1975, is a single-stranded DNA virus belonging to the Parvoviridae family of viruses (1) and it is identified as one of the smallest viruses to infect the mammalian cell (2).

Parvoviruses are species specific and humans are exclusively affected by the type B19 (1).

Transmission of the disease can occur via:

  • respiratory route
  • hand-to-mouth contact
  • blood products
  • vertically from the mother to the fetus (3)

Replication of the virus occurs in rapidly dividing erythroid progenitor cells although other target cells have also been identified e.g – myocardial tissue (1).

The most typical manifestations of parvovirus B19 infection are

  • erythema infectiosum (ie, fifth disease)
  • transient aplastic crisis
  • chronic red cell aplasia
  • arthropathy
  • nonimmune hydrops fetalis (3)

Fifth disease is due to infection with human erythrovirus (formerly parvovirus) type B19, and tends to occur in school-aged children, sometimes occurring in epidemics. As the alternative name indicates, the maculopapular rash associated with this disease often resembles slap marks on the cheeks.

One episode of infection will provide life long immunity in individuals (1).

Click here for example images of this condition



The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions LtdĀ®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions LtdĀ® receives funding from advertising but maintains editorial independence. GPnotebook stores small data files on your computer called cookies so that we can recognise you and provide you with the best service. If you do not want to receive cookies please do not use GPnotebook.