The majority of cases of CLL result from malignant transformation of a B cell; less frequently, of a T cell. In any particular case B or T cell clonality can be established using DNA probes. The malignant lymphocyte is indistinguishable morphologically, from a normal small, relatively mature lymphocyte.
Smear cells are common which have:
CLL differs from multiple myeloma in that CLL is derived from small, relatively mature lymphocytes whereas multiple myeloma is derived form bone marrow plasma cells and their precursors.
Add information to this page that would be handy to have on hand during a consultation, such as a web address or phone number. This information will always be displayed when you visit this page