Gout is considered a progressive disease which will eventually end up as severe tophaceous gout (with joint damage and significant functional impairment) in the absence of effective long-term therapy (1).
The disease is commonly divided into the following phases:
- initial asymptomatic hyperuricaemia
- recurrent acute gout attacks interspersed with asymptomatic intercritical periods
- chronic symptomatic tophaceous gout (with inadequately treated hyperuricemia) (1).
- it should be noted that these are not discrete phases but a continuum (1).
- (1) Doherty M. New insights into the epidemiology of gout. Rheumatology (Oxford). 2009;48 Suppl 2:ii2-ii8
Last reviewed 07/2021