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Calculation of warfarin maintenance dose based on rapid anticoagulation regime with 10mg initial dose

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

This is based on the INR taken on the morning of day 4, ie after 3 doses of warfarin. Check with local guidance before prescribing.

Example guidance:

INR

Predicted maintenance dose

 

< 1.4

 

>8

1.4

8

1.5

7.5

1.6-1.7

7

1.8

6.5

1.9

6

2.0-2.3

5.5

2.4-2.6

4.5

2.7-3.0

4

3.1-3.5

3.5

3.6-4.0

3

4.1-4.5

miss out next day's dose then 2mg per day

>4.5

miss out next two days' dose then 1mg per day

Ref: Prescribers' Journal (1997), 37 (3),173-9.

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