This site is intended for healthcare professionals
Login | Register (NOW FREE)

Medical search

lead time bias

FREE subscriptions for doctors and students... click here
You have 3 open access pages.

Lead time is the period between early detection of disease and the time of its usual clinical presentation.


When evaluating the effectiveness of the early detection and treatment of a condition, the lead time must be subtracted from the overall survival time of screened patients to avoid lead time bias. Otherwise early detection merely increases the duration of the patients' awareness of their disease without reducing their mortality or morbidity. Numerous cancer screening procedures were thought to improve survival until lead time bias was addressed.

The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions LtdĀ®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions LtdĀ® receives funding from advertising but maintains editorial independence. GPnotebook stores small data files on your computer called cookies so that we can recognise you and provide you with the best service. If you do not want to receive cookies please do not use GPnotebook.