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Pharmacokinetics

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

  • digoxin half-life = 40 hours; elimination = renal; plasma concentration < 3 ng/ml

  • digitoxin half-life = 5 days; elimination = metabolic; plasma concentration < 30 ng/ml

The plasma concentrations are those below which the drug should be kept to minimise the risk of toxicity.

Reference:

  • 1) Oxford Textbook of Clinical Pharmacology and Drug Therapy. Third Edition. Editors D.G. Grahame-Smith and J.K. Aronson. Oxford: Oxford University Press, 2002

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