Last reviewed 01/2018

This is essential after an episode of PCP, or when CD4 positive counts drop below 200/microlitre or less than 20% of total lymphocyte count.

The most effective agents are a combination of Trimethoprim and Sulphamethoxazole (co-trimoxazole). If this is poorly tolerated however aerosolized pentamidine or dapsone may be used (note that dapsone may cause haemolytic anaemia and is contra-indicated in G6PD deficiency).