epidemiology

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The incidence of chronic myeloid leukaemia (CML) is around 1–2 cases per 100 000 population/year without an obvious geographical difference (1).

  • in England and Wales
    • CML accounts for more than one in six leukaemias in adults with around 600 new cases being registered each year
    • the annual case rates are 1.0 per 100,000 men and 0.8 per 100,000 women
    • around 2660 people have CML (2)
  • accounts for 15-20% of cases of leukaemias in developed countries
  • the incidence increases with age (3), median age at diagnosis is around 65 years (4)
  • it affects men more than women and there seems to be a survival advantage in women over men (4)
  • chronic granulocytic leukaemia is the most common variant of CML

Reference:

Last reviewed 01/2018