continuation phase of treatment of active TB

Last reviewed 01/2018

Seek specialist advice and consult local guidelines.

The continuation phase of treatment of tuberculosis consists of double therapy for four months:

  • rifampicin

  • isoniazid (with pyridoxine)

·Patients with active meningeal TB should be offered: -

  • isoniazid (with pyridoxine), rifampicin, pyrazinamide and ethambutol for 2months

  • then isoniazid (with pyridoxine) and rifampicin for a further 10 months.

  • a glucocorticoid

The summary of product characteristics must be consulted before the aforementioned drugs are prescribed.


  1. NICE (January 2016). Tuberculosis