alanine aminotransferase

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Alanine aminotransferase is a cytoplasmic enzyme that is predominantly hepatic in origin. Therefore, changes tend to parallel those of aspartate aminotransferase, but ALT is more liver-specific.

Mild hepatic injury tends to increase the ratio of cytoplasmic ALT to AST; more severe disease reverses the trend.

Last reviewed 01/2018

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