Last reviewed 07/2021
Cushing's syndrome refers to the set of clinical features resulting from persistently and inappropriately elevated levels of glucocorticoid. Usually the condition is iatrogenic.
Spontaneous Cushing's syndrome is rare, more common in females, and in about two-thirds of cases, due to Cushing's disease, that is due to pituitary-dependent adrenal hyperplasia.
Identification of the cause of the condition is essential to effective management.