treatment of staphylococcal pneumonia

Last reviewed 01/2018

Antibiotic treatment should be started after blood and sputum has been taken for culture. Initial therapy is often blind.

Consult with a bacteriologist about appropriate drug treatment if in doubt:

  • penicillin-sensitive
    • first choice: benzylpenicillin
    • alternative: erythromycin

  • penicillinase producing
    • first choice: flucloxacillin
    • alternative: dependent on local sensitivities

Treatment for staphylococcal pneumonia may be with flucloxacillin 250 mg 4 times daily by mouth or IV until improvement. In severe infections, doses may be doubled.