genetic factors

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Genetic factors are thought to be important in essential hypertension, inheritance being multigenic:

  • twins show a greater concordance than spouses

  • twin studies indicate that up to 60% of the variability in blood pressure is related to inheritable factors

  • close relative of patients with a blood pressure 50 mm Hg above the mean, themselves have a blood pressure on average 14 mm Hg above the mean

Last reviewed 01/2018