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Clinical features

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The classical features are:

  • rheumatoid arthritis
  • splenomegaly
  • neutropenia, manifesting with recurrent infections

Other associated abnormalities include:

  • normochromic, normocytic anaemia
  • thrombocytopenia
  • lymphadenopathy
  • skin pigmentation and ulceration

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