anti-Mi2

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  • autoantibodies against non-histone nuclear proteins involved in transcription processes are typical in myositis, antibodies to Mi-2 are more specific
    • found more frequently in dermatomyositis than polymyositis
    • presence of antibodies to Mi-2 has been correlated with a good response to treatment

    Reference:

    • (1) Sherley-Dale A. Serum autoantibodies and connective tissue disorders. Dermatology in Practice (April 2008); 16(1).

    Last reviewed 01/2018

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