Last reviewed 01/2018

  • autoantibodies against non-histone nuclear proteins involved in transcription processes are typical in myositis, antibodies to Mi-2 are more specific
    • found more frequently in dermatomyositis than polymyositis
    • presence of antibodies to Mi-2 has been correlated with a good response to treatment


    • (1) Sherley-Dale A. Serum autoantibodies and connective tissue disorders. Dermatology in Practice (April 2008); 16(1).