- autoantibodies against non-histone nuclear proteins involved in transcription
processes are typical in myositis, antibodies to Mi-2 are more specific
- found more frequently in dermatomyositis than polymyositis
- presence of antibodies to Mi-2 has been correlated with a good response to treatment
- (1) Sherley-Dale A. Serum autoantibodies and connective tissue disorders. Dermatology in Practice (April 2008); 16(1).
Last reviewed 01/2018