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Differential diagnosis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

TEN should be differentiated from the following exfoliating, desquamating, or blistering diseases:

  • Staphylococcal scalded skin syndrome (SSSS) - blistering is more superficial and involvement of the mucous membrane is less common than in TEN
  • Stevens-Johnson syndrome (SJS) - Detachment <10% of body surface with widespread purpuric or erythematous macules or both and flat atypical target lesions
  • Bullous erythema multiforme - Detachment <10% of body surface area and localised target lesions or raised atypical targets
  • Bullous pemphigoid
  • Pemphigus

Reference:

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