ezetimibe 10mg versus 5mg dose

Last reviewed 01/2018

Ezetimibe 5mg versus 10mg dose

  • there is evidence that ezetimibe 5mg (split 10mg tablet) has similar efficacy to ezetimibe 10mg and greater tolerability (1,2)
    • in a study of 272 patients, 197 had evaluable baseline and posttreatment LDL-C (55 taking the 5-mg dose and 142 taking the 10-mg dose)
      • the effects of ezetimibe 5 and 10 mg on all lipid parameters were similar. Ezetimibe 10 mg reduced LDL-C by 26.1%, whereas 5 mg reduced LDL-C by 25.8% (1)