uric acid levels in acute gout

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Uric acid levels in acute gout

  • serum urate levels should be checked to confirm hyperuricaemia and to monitor response to treatment
    • however, a degree of caution is required in interpreting the results. Serum urate levels tend to decrease during an acute attack of gout and rise again as inflammation settles
    • therefore
      • if the serum urate level is found to be normal during a suspected attack of gout it should be repeated once the attack has resolved

Conversely, as most people with hyperuricaemia do not develop gout, concurrent joint symptoms and hyperuricaemia should not be considered to equate with gout unless the clinical presentation is typical or MSU crystals have been identified on aspirated synovial fluid. Renal function should also be assessed.


  1. Arthritis Research UK (2011). Hands On (9) - gout: presentation and management in primary care

Last reviewed 01/2018