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Diagnosis of Japanese Encephalitis infection

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

diagnosis

Laboratory diagnosis of JEV infection includes:

  • IgM capture enzyme-linked immunosorbent assay (ELISA) of serum or CSF
    • measurement of JEV-specific IgM can be carried out in CSF of most patients by 4 days after onset of symptoms and in serum by 7 days after onset (1)
  • other laboratory findings may include: leukocytosis, mild anaemia and hyponatraemia
  • in lumbar puncture CSF typically has
    • a mild to moderate pleocytosis with a lymphocytic predominance
    • slightly elevated protein
    • normal ratio of CSF to plasma glucose (1

Reference:

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