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Investigations in acute diverticulitis

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Investigation of suspected acute diverticulitis


Primary care


For people with suspected uncomplicated acute diverticulitis who are not referred for same-day hospital assessment:

  • reassess in primary care if their symptoms persist or worsen and
  • consider referral to secondary care for further assessment

Secondary care (1)

For people with suspected complicated acute diverticulitis who have been referred for same-day hospital assessment, offer a full blood count, urea and
electrolytes test and C-reactive protein test.


If the person with suspected complicated acute diverticulitis has raised inflammatory markers, offer a contrast CT scan within 24 hours of hospital
admission to confirm diagnosis and help plan management. If contrast CT is contraindicated, perform one of the following:

  • a non-contrast CT or
  • an MRI or
  • an ultrasound scan, depending on local expertise

If inflammatory markers are not raised, think about the possibility of alternative diagnoses.

A review suggests (2):

  • in patients presenting with suspected acute diverticulitis
    • an abdominal computed tomography scan should be performed to confirm the diagnosis, to determine the severity of disease, and to rule out an alternative diagnosis
    • is most important for the first presentation and less important for a stereotypical mild recurrence
  • in centers with expertise in ultrasonography
    • a step-up approach with computed tomography performed after an inconclusive or negative ultrasound scan may be considered
    • computed tomography
      • performs better in obese patients and is better able to assess the distal sigmoid colon, which is difficult to visualize with transabdominal ultrasonography
  • colonoscopy
    • should be performed six to eight weeks after a diagnosis of complicated diverticulitis or first episode of uncomplicated diverticulitis
    • in the absence of alarm symptoms, a colonoscopy does not need to be repeated if a high quality examination has been performed in the previous year
    • patients with recurrent uncomplicated diverticulitis and no alarm symptoms should follow routine colorectal cancer screening and surveillance intervals
  • ongoing gastrointestinal symptoms
    • common after recovery from the acute phase of diverticulitis, and alternative diagnoses should be considered
    • repeat imaging and colonoscopy is often necessary to rule out a misdiagnosis or ongoing inflammation

Reference:

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